| Proposal 1: | | | To elect six directors to serve for the ensuing year. | |
| Proposal 2: | | | To approve a non-binding advisory resolution regarding executive compensation. | |
| Proposal 3: | | | To ratify the selection by the Audit Committee of the Board of Directors Grant Thornton LLP as the independent registered public accounting firm of the Company for its fiscal year ending December 31, 2021. | |
Proposal
|
| |
Board
Recommendation |
| |
Vote
Required |
| |
Broker
Discretionary Voting Allowed |
|
Proposal 1: Elect six directors to serve until the 2022 Annual Meeting of Stockholders. | | |
FOR
|
| |
Majority Votes
Cast |
| |
No
|
|
Proposal 2: Approval of a non-binding advisory resolution regarding executive compensation. | | |
FOR
|
| |
Majority Votes
Cast |
| |
No
|
|
Proposal 3: Ratify the appointment of Grant Thornton LLP as our independent registered public accounting firm for the year ending December 31, 2021. | | |
FOR
|
| |
Majority Votes
Cast |
| |
Yes
|
|
| | We provide Internet proxy voting to allow you to vote your shares online, with procedures designed to ensure the authenticity and correctness of your proxy vote instructions. However, please be aware that you must bear any costs associated with your Internet access, such as usage charges from Internet access providers. | | |
Name
|
| |
Age
|
| |
Positions and Offices
Held With the Company |
|
George W. Bickerstaff, III | | |
65
|
| |
Director
|
|
Deborah L. Birx, M.D. | | |
64
|
| |
Director
|
|
Mark A. DiPaolo, Esq. | | |
50
|
| |
Director
|
|
Jules Haimovitz | | |
70
|
| |
Director
|
|
Odysseas D. Kostas, M.D. | | |
46
|
| |
Director
|
|
Sarah J. Schlesinger, M.D. | | |
61
|
| |
Director
|
|
Director
|
| |
Audit
|
| |
Compensation
|
| |
Nominating/
Corporate Governance |
|
George W. Bickerstaff, III | | |
X
|
| |
X
|
| |
X
|
|
Mark A. DiPaolo, Esq. | | | | | |
X
|
| |
X
|
|
Jules Haimovitz | | |
X
|
| |
X
|
| |
X
|
|
Odysseas D. Kostas, M.D. | | |
X
|
| | | | |
X
|
|
Sarah J. Schlesinger, M.D. | | |
X
|
| |
X
|
| |
X
|
|
Total meetings in fiscal year 2020 | | |
6
|
| |
4
|
| |
4
|
|
Director
|
| |
Audit
|
| |
Compensation
|
| |
Nominating/Corporate
Governance |
|
George W. Bickerstaff, III | | |
X*
|
| |
X
|
| | | |
Deborah L. Birx, M.D. | | |
X
|
| | | | |
X
|
|
Jules Haimovitz | | |
X
|
| |
X*
|
| |
X
|
|
Sarah J. Schlesinger, M.D. | | | | | |
X
|
| |
X*
|
|
Name
|
| |
Fees Earned or
Paid in Cash ($)(1) |
| |
Stock
Awards ($)(2) |
| |
Total
($) |
| |||||||||
George W. Bickerstaff, III(4)
|
| | | | 101,712 | | | | | | 224,996 | | | | | | 326,708 | | |
Odysseas D. Kostas, M.D.(3)
|
| | | | 87,717 | | | | | | 224,996 | | | | | | 312,713 | | |
Mark A. DiPaolo(3)
|
| | | | 64,144 | | | | | | 224,996 | | | | | | 289,140 | | |
Jules Haimovitz(4)
|
| | | | 97,785 | | | | | | 224,996 | | | | | | 322,781 | | |
Sarah J. Schlesinger
|
| | | | 73,071 | | | | | | 224,996 | | | | | | 298,067 | | |
| | |
Fiscal Year
Ended December 31, |
| |||||||||
| | |
2020
|
| |
2019
|
| ||||||
| | |
(in thousands)
|
| |||||||||
Audit Fees(1)
|
| | | $ | 446 | | | | | $ | 278 | | |
Audit Related Fees
|
| | | | — | | | | | | — | | |
Tax Fees
|
| | | | — | | | | | | — | | |
All Other Fees
|
| | | | — | | | | | | — | | |
Total Fees
|
| | | $ | 446 | | | | | $ | 278 | | |
| | | |
George W. Bickerstaff, III, Chairperson
Jules Haimovitz Dr. Sarah J. Schlesinger, M.D. |
|
Name
|
| |
Age
|
| |
Positions Held
|
|
Pavel Raifeld | | | 37 | | | Chief Executive Officer | |
Marianne Zhen | | | 52 | | | Chief Accounting Officer | |
Name and Address of Beneficial Owner(1)
|
| |
Number of Shares
|
| |
Percent of Total
Outstanding Common Stock |
| ||||||
5% Stockholders | | | | | | | | | | | | | |
GlaxoSmithKline plc(2)
980 Great West Road Brentford Middlesex TW8 9GS United Kingdom |
| | | | 32,005,260 | | | | | | 31.6% | | |
BlackRock, Inc.(3)
55 East 52nd Street New York, NY 10022 |
| | | | 11,160,546 | | | | | | 11.0% | | |
Renaissance Technologies LLC(4)
800 Third Avenue New York, NY 10022 |
| | | | 7,881,802 | | | | | | 7.8% | | |
The Vanguard Group(5)
100 Vanguard Blvd. Malvern, PA 19355 |
| | | | 6,595,483 | | | | | | 6.5% | | |
Sarissa Capital Management LP
660 Steamboat Road Greenwich, CT 06830 |
| | | | 6,414,000 | | | | | | 6.3% | | |
Directors and Officers | | | | | | | | | | | | | |
George W. Bickerstaff, III, Director(6)
|
| | | | 87,078 | | | | | | * | | |
Mark A. DiPaolo, Esq., Director(7)
|
| | | | 58,082 | | | | | | * | | |
Jules Haimovitz, Director(8)
|
| | | | 70,282 | | | | | | * | | |
Odysseas D. Kostas, M.D., Director(9)
|
| | | | 62,078 | | | | | | * | | |
Sarah J. Schlesinger, M.D., Director(10)
|
| | | | 58,082 | | | | | | * | | |
Name and Address of Beneficial Owner(1)
|
| |
Number of Shares
|
| |
Percent of Total
Outstanding Common Stock |
| ||||||
Deborah L. Birx, M.D., Director(11)
|
| | | | 1,612 | | | | | | * | | |
Pavel Raifeld, Chief Executive Officer(12)
|
| | | | 62,500 | | | | | | * | | |
Marianne Zhen, Chief Accounting Officer
|
| | | | 38,399 | | | | | | * | | |
All current executive officers and directors as a group (8 persons) (13)
|
| | | | 438,113 | | | | | | * | | |
Name and Principal Position
|
| |
Year
|
| |
Salary
($)(1) |
| |
Bonus
($)(2) |
| |
Stock
Awards ($)(3) |
| |
Option
Awards ($)(3) |
| |
Non-Equity
Incentive Plan Compensation ($) |
| |
All Other
Compensation ($)(4) |
| |
Total
($) |
| ||||||||||||||||||||||||
(a)
|
| |
(b)
|
| |
(c)
|
| |
(d)
|
| |
(e)
|
| |
(f)
|
| |
(g)
|
| |
(i)
|
| |
(j)
|
| ||||||||||||||||||||||||
Pavel Raifeld
Chief Executive Officer |
| | | | 2020 | | | | | | 222,000(5) | | | | | | 132,968 | | | | | | — | | | | | | 1,570,000 | | | | | | — | | | | | | 19,000 | | | | | | 1,943,968 | | |
Marianne Zhen
Chief Accounting Officer |
| | | | 2020 | | | | | | 284,625 | | | | | | 128,081 | | | | | | 124,996 | | | | | | — | | | | | | — | | | | | | 21,167 | | | | | | 558,869 | | |
| | | 2019 | | | | | | 275,000 | | | | | | 123,750 | | | | | | 125,001 | | | | | | — | | | | | | 7,500 | | | | | | 20,667 | | | | | | 551,918 | | | ||
| | | 2018 | | | | | | 239,602 | | | | | | 77,524 | | | | | | 124,946 | | | | | | — | | | | | | 15,000 | | | | | | 20,333 | | | | | | 477,405 | | | ||
Geoffrey L. Hulme
Interim Principal Executive Officer |
| | | | 2020 | | | | | | 120,319(6) | | | | | | — | | | | | | 224,996(7) | | | | | | — | | | | | | — | | | | | | 370,927(8) | | | | | | 716,242 | | |
| | | 2019 | | | | | | 300,000 | | | | | | 180,000 | | | | | | 355,768 | | | | | | — | | | | | | — | | | | | | 20,667 | | | | | | 856,435 | | | ||
| | | 2018 | | | | | | 184,375 | | | | | | 110,323 | | | | | | — | | | | | | — | | | | | | — | | | | | | 7,500 | | | | | | 302,198 | | |
| | | | | | | | |
Estimated Possible
Payouts Under Non-Equity Incentive Plan Awards |
| |
All Other
Stock Awards: Number of Shares or Units (#) |
| |
Grant Date
Fair Value of Stock Awards ($) |
| |||||||||||||||||||||
Name
|
| |
Grant
Date |
| |
Threshold
(#) |
| |
Target
(#) |
| |
Maximum
(#) |
| ||||||||||||||||||||||||
Pavel Raifeld
|
| | | | 5/20/2020 | | | | | | — | | | | | | — | | | | | | — | | | | | | 250,000(1) | | | | | | 1,570,000 | | |
Marianne Zhen
|
| | | | 2/3/2020 | | | | | | — | | | | | | — | | | | | | — | | | | | | 8,741(2) | | | | | | 124,996 | | |
Geoffrey L. Hulme
|
| | | | 2/3/2020 | | | | | | — | | | | | | — | | | | | | — | | | | | | 15,734(3) | | | | | | 224,996 | | |
| | | | | | | | |
Option Awards
|
| |
Stock Awards
|
| ||||||||||||||||||||||||||||||
Name
|
| | | | | | | |
Number of
Securities Underlying Unexercised Options (#) Exercisable |
| |
Number of
Securities Underlying Unexercised Options (#) Unexercisable |
| |
Option
Exercise Price ($) |
| |
Option
Expiration Date |
| |
Number
of Shares or Units of Stock That Have Not Vested (#) |
| |
Market
Value of Shares or Units of Stock That Have Not Vested ($)(1)(2) |
| ||||||||||||||||||
(a)
|
| | | | | | | |
(b)
|
| |
(c)
|
| |
(e)
|
| |
(f)
|
| |
(g)
|
| |
(h)
|
| ||||||||||||||||||
Pavel Raifeld
|
| | |
|
(3)
|
| | | | | — | | | | | | 250,000 | | | | | | 14.10 | | | | | | 5/20/2030 | | | | | | — | | | | | | — | | |
Marianne Zhen
|
| | |
|
(4)
|
| | | | | — | | | | | | — | | | | | | | | | | | | | | | | | | 8,741 | | | | | | 108,301 | | |
| | | |
|
(5)
|
| | | | | — | | | | | | — | | | | | | | | | | | | | | | | | | 4,586 | | | | | | 56,821 | | |
| | | |
|
(6)
|
| | | | | — | | | | | | — | | | | | | | | | | | | | | | | | | 556 | | | | | | 6,889 | | |
| | | |
|
(7)
|
| | | | | — | | | | | | — | | | | | | | | | | | | | | | | | | 1,938 | | | | | | 24,012 | | |
| | | |
|
(8)
|
| | | | | — | | | | | | — | | | | | | | | | | | | | | | | | | 625 | | | | | | 7,744 | | |
Geoffrey L. Hulme
|
| | | | | | | | | | — | | | | | | — | | | | | | | | | | | | | | | | | | — | | | | | | — | | |
| | | | | | | | |
Stock Awards
|
| |||||||||
Name
|
| |
Security
|
| |
Number of Shares
Acquired on Vesting (#) |
| |
Value Realized on
Vesting ($)(1) |
| |||||||||
Marianne Zhen
|
| | | | INVA | | | | | | 8,807 | | | | | | 121,313 | | |
Geoffrey L. Hulme
|
| | | | INVA | | | | | | 4,587 | | | | | | 68,347 | | |
Name
|
| |
Bonus for
Year of Termination ($) |
| |
Cash
Severance ($) |
| |
Vacation Payout ($)
|
| |
Restricted
Stock or Options that Vest ($) |
| |
Health and
Welfare ($) |
| |
Total
($) |
| ||||||||||||||||||
Pavel Raifeld | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Termination Without Cause
|
| | | | 132,968(1) | | | | | | 180,000 | | | | | | 12,754 | | | | | | — | | | | | | — | | | | | | 325,722 | | |
Involuntary Termination in Connection with a Change in Control
|
| | | | 132,968 | | | | | | 180,000 | | | | | | 12,754 | | | | | | —(2) | | | | | | — | | | | | | 325,722 | | |
Marianne Zhen | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Termination Other than for
Misconduct or Resignation for Good Reason |
| | | | 128,081(3) | | | | | | 284,625(4) | | | | | | 47,894 | | | | | | — | | | | | | 30,778(5) | | | | | | 491,378 | | |
Involuntary Termination in Connection with a Change in Control
|
| | | | 128,081(3) | | | | | | 412,706(6) | | | | | | 47,894 | | | | | | 203,766(7) | | | | | | 30,778(5) | | | | | | 823,225 | | |
Plan Category
|
| |
Number of securities to be
issued upon exercise of outstanding options, warrants and rights |
| |
Weighted-average
exercise price of outstanding options, warrants and rights |
| |
Number of securities
remaining available for future issuance under equity compensation plans (excluding securities reflected in column (a)) |
| |||||||||
| | |
(a)
|
| |
(b)
|
| |
(c)
|
| |||||||||
Equity compensation plans approved by security holders
|
| | | | 1,239,744(1) | | | | | $ | 22.28(2) | | | | | | 5,033,354(3) | | |
| | | | | 1,239,744 | | | | | | | | | | | | 5,033,354 | | |